ĐẶC ĐIỂM DỊCH TỄ HỌC, LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ HỘI CHỨNG VIÊM ĐA HỆ THỐNG Ở TRẺ EM LIÊN QUAN ĐẾN COVID-19

Abstract

Objectives: To describe the epidemiological, clinical, paraclinical characteristic and treatment outcomes of the multisystem inflammatory syndrome in children (MIS-C) related to Covid -19 at the Cardiology – Rheumatology department of Children’s Hospital 2. Methods: Descriptive case series with analysis on 105 cases diagnosed with MIS -C who were admitted for treatment at the Cardiology – Rheumatology department of Children’s Hospital 2 from November 2021 to the end of March 2022. Results: MIS -C mostly occured in children aged 5 -11, with a higher prevalence in males. Clincal symptoms: fever (100%), gastroinstestinal symptoms (90,5%), red eye (80,9%), rash (70,5%). About a quater of the cases had severe presentations with hypotension or shock. Paraclinical findings showed elevated imflamatory marker (CRP, ERS, LDH, D -dimer). 50% of the patients had thrombocytopenia at diagnosis. More than two – thirds of the cases had cardiac involvement on echocardiography, including coronary artery dilation, left ventricular dysfunction, and pericardial effusion. Nearly 50% of children with MIS -C had Kawasaki -like symptoms. Treatment included IVIG, Steroids, Aspirin, and anticoagulants depending on the case. No deaths and the average hospital stay was one week. Conclusion: MIS-C occurs 4 to 8 weeks after a child has been infected with Covid-19. Therefore, when a patient presents with fever and gastrointestinal symptoms, it is important to consider MIS-C to avoid missing the diagnosis.