ĐẶC ĐIỂM VIÊM PHÚC MẠC Ở BỆNH NHI SUY THẬN MẠN GIAI ĐOẠN CUỐI ĐANG THẨM PHÂN PHÚC MẠC TẠI BỆNH VIỆN NHI ĐỒNG 2

Abstract

Background: Peritonitis is one of the most serious complications in peritoneal dialysis patients diagnosed with end-stage renal disease. Peritonitis may lead to permanent membrane damage, therapeutic failure and remains the primary fatal reason in children on peritoneal dialysis. Consequently, our study was done to describe the rate, clinical features, laboratory results, treatment, and outcomes of peritonitis. Methods: A case series study. Results: Peritonitis occurred in 16 patients of 49 chronic peritoneal dialysis patients (32,6%) with 29 episodes, in total. The peritonitis rate was 0,3 episodes per patient-year. Almost peritonitis episodes occurred after the first of peritoneal dialysis therapy (79,3%). The most popular symptom of peritonitis was cloudy effluent and Staphylococcus aureus was the most common cultured agent. Cefepim was the primary initial antibiotic used (37,5%). Following peritonitis, the rate of peritonitis-associated catheter removal, hemodialysis transfer, repeat peritonitis, and relapsing peritonitis were 31,25%; 25%; 25%, and 12%, respectively. Conclusions: Peritonitis was the most common complication of peritoneal dialysis patients, especially after the first therapeutic year with cloudy effluent as the most popular symptom. This also remains the primary reason leading to therapeutic failure with a high rate of peritonitis-associated catheter removal and hemodialysis transfer.