ĐẶC ĐIỂM TỔN THƯƠNG ĐỘNG MẠCH VÀNH TRÊN CẮT LỚP VI TÍNH ĐA DÃY ĐẦU DÒ Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÍP 2

Abstract

Objective: The study aimed to describe the image characteristics and incidence of coronary artery lesions on coronary computed tomography angiography in patients with type 2 diabetes and explore the relationship between lesion characteristics coronary artery with some type 2 diabetic patient characteristics. Methods: This is a retrospective, cross-sectional study. All patients underwent coronary computed tomography angiography at Thong Nhat Hospital, Ho Chi Minh City from September 2022 to September 2023. Results: There were 294 patients who underwent coronary CT angiography, including 147 patients with type 2 diabetes (92 men, accounting for 62.6%, 55 women, accounting for 37.4%) and 147 patients without diabetes (including 93, males accounted for 63.3% and 54 females accounted for 36.7%). The mean age of the non-diabetic group was 61.7 ± 10.5, significatively lower than the mean age of the diabetic group which was 68.4 ± 8.9 (p < 0.001). The non-diabetic group had less coronary artery damage and the number of damaged branches was also statistically significant compared to the diabetic group (p=0.002). The rate of significant narrowing of coronary artery branches: anterior descending artery (LAD), Left circumflex artery (LCX), right coronary artery (RCA) (narrowing ≥50%) in the non-diabetic group was statistically significantly lower than the diabetic group. except for the left main artery (LM). Among coronary artery branches narrowed > 50%, LAD stenosis contributed for the highest rate, in the diabetic group (41.5%) and the non-diabetic group (27.2%). The Agatston calcification score in the diabetic group was 234.9±395.8, higher than the non-diabetic group (106.7±334.2). The calcification score in the coronary branches in the diabetic group were statistically significantly higher than the non-diabetic group (p<0.001). The area under the curve (AUC) for the calcification score in predicting ≥50% coronary stenosis is 0,839, with a cut-off threshold of 88 points, with the highest sensitivity and specificity in diagnosis of 74,3% and 79,5%, respectively. Only the duration of diabetes is related to coronary artery stenosis (r = 0, 38). ​Conclusion: coronary CT angiography plays an important role in detecting coronary calcification, predicting the level of coronary artery stenosis and diagnosing coronary artery stenosis, especially in diabetic patients.