CLINICAL FEATURES, PARA-CLINICAL FEATURES AND RESULTS OF TREATMENT OF PERTUSSIS AT THE DEPARTMENT OF TROPICAL DISEASE, NGHE AN OBSTETICS AND PEDIATRIC HOSPITAL

Anh Vinh Ngô , Mạnh Hùng Võ

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Abstract

Objectives: Describe the clinical, paraclinical characteristics and treatment results of pertussis at Nghe An Obstetrics and Children's Hospital in 2017. Subjects and research methods: 100 patients, who were diagnosed with pertussis according to the criteria of Global whooping cough conference 2011, were inpatient treatment at the Department of Tropical Diseases - Nghe An Obstetrics and Pediatrics Hospital. Results: Patients’s ages under 3 months accounted for the highest proportion with 74%. All cases had symptoms of cough (100%) with paroxysmal cough accounting for 95%, cough with red face and cyanosis accounting for 68%. 13% of cases had elevated white blood cells ≥30,103/ml, 52% of which had lymphocyte counts ≥ 70%. Regarding the treatment results, most patients progressed well (95%) with an average treatment time of 10.03 ± 8.3 days. The rate of complications is 63%, of which the most common is pneumonia (46%). The results of multivariate regression analysis showed that the following factors: patient’s age under 3 months, pneumonia and peripheral blood leukocyte increase above 30,103/mm³ are predictive factors for severe pertussis. Conclusion: Cough is a characteristic sign of whooping cough found in all cases. Factors including age under 3 months, pneumonia and peripheral blood white blood cell count above 30,103/mm³ are factors that are independently related to severe pertussis.

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References

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