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CLINICAL CHARACTERISTICS OF PATIENTS WITH MYELIN OLIGODENDROCYTE GLYCOPROTEIN ANTIBODY-ASSOCIATED DISEASE ADMITTED AT NEUROLOGY DEPARTMENT, UNIVERSITY MEDICAL CENTER AT HO CHI MINH CITY FROM 1/2021-12/2023
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Abstract
Objectives: To analyzed clinical characteristics of patients myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) admitted at neurology department, university medical center at ho chi minh city from 1/2021-12/2023. Methods: A descriptive retrospective study was performed collecting 18 patients associated with positivity of anti-MOG antibody. Results: of 18 patients, female/male ratio ≈ 1.25:1 and median age was 37.5 years old, half of patients had optic neuritis as clinical phenotype onset. Median age onset was 36.5 years old. The majority of patients responsed to acute treatment and followed prevention treatment with Mycophenolate mofetil. 33.3% relapse recorded after first year follow-up. Conclusion: MOGAD is rare disease characterized by good recovery after aucte treatment but high relapse rate.
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2. Jurynczyk M, Messina S, Woodhall MR, Raza N, Everett R, Roca-Fernandez A, et al. Clinical presentation and prognosis in MOG-antibody disease: a UK study. Brain 2017;140:3128-3138.
3. de Mol CL, Wong Y, van Pelt ED, Wokke B, Siepman T, Neuteboom RF, et al. The clinical spectrum and incidence of anti-MOG-associated acquired demyelinating syndromes in children and adults. Mult Scler 2020;26:806-814.
4. Kim KH, Kim S-H, Hyun J-W, Kim HJ. Clinical and Radiological Features of Myelin Oligodendrocyte Glycoprotein-Associated Myelitis in Adults. J Clin Neurol 2022;18:280-289.