CÁC YẾU TỐ LIÊN QUAN TỔN THƯƠNG TIM TRÊN BỆNH NHI HỘI CHỨNG VIÊM ĐA HỆ THỐNG LIÊN QUAN ĐẾN COVID-19

Abstract

Objectives: To describe the characteristic cardiac lesions and factors related to cardiac lesions in MIS-C at different time points (hospitalization, discharge, and 12 weeks after discharge). Methods: Descriptive case series study with analysis on 105 cases diagnosed with MIS -C who were admitted for treatment at the Cardiology – Rheumatology department of Children’s Hospital 2 from November 2021 to the end of March 2022. Results: Cardiac lesions were found in 2/3 of the MIS -C patients. These included coronary artery dilation (42,8%), left ventricular dysfuntion (24,8%), and pericardial effusion (9,5%). Conduction system disorders with prolonged PR interval were only found in 3 cases. Thrombocytopenia at diagnosis was noted to be associated with cardiac lesions. 50% of cardiac lesion cases recovered after 12 weeks of follow up (pericardial effusion and left ventricular dysfunction recovered completely, some cases of coronary artery lesions persisted). Conclusion: Thrombocytopenia at diagnosis was noted to be associated with cardiac lesions. Most cardiac injury in MIS -C patients recovered after 12 weeks of follow up.