NGHIÊN CỨU MỘT SỐ ĐẶC ĐIỂM GIẢI PHẪU BỆNH VÀ DƯỚI TÍP PHÂN TỬ CỦA UNG THƯ BIỂU MÔ VÚ XÂM NHẬP TẠI BỆNH VIỆN UNG BƯỚU THANH HÓA

Abstract

Background: Breast cancer is the most common type of cancer in women, of which invasive breast carcinoma (IBC) is the type with the highest proportion. IBC is diverse in histopathological characteristics and molecular types, so there are different treatment methods and prognosis. In the world and at central hospitals in Vietnam, there are many studies on breast cancer, but in Thanh Hoa there are very few studies on this disease. Purpose: “Describe some pathological features and molecular subtypes of invasive breast carcinoma”. Methods: Research subjects and methods: Descriptive study on 164 IBC cases at Thanh Hoa Oncology Hospital from February 2022 to September 2023. Results: Invasive breast carcinoma of no special type (86.6%), histological grade II (73.2%) were the characteristics with the highest proportion. 53.7% of cases had axillary lymph node metastasis, 4.3% of cases had nerve invasion. The Her2 positive type accounts for the highest proportion (24.4%), the lowest are the luminal type A and triple negative. Conclusion: The histopathological characteristics and molecular subtypes of IBC at Thanh Hoa Oncology Hospital are very diverse, which is a premise for conducting more in-depth research on breast cancer.