BÁO CÁO LOẠT CA: VIÊM PHỔI CỘNG ĐỒNG NẶNG DO ACINETOBACTER BAUMANNII TẠI BỆNH VIỆN NHÂN DÂN GIA ĐỊNH

Abstract

Objective: We investigated the risk factors, epidemiology, clinical and microbiological, characteristics of severe community-acquired pneumonia (CAP) due to AB at Nhan Dan Gia Dinh Hospital, in Ho Chi Minh City. Method: We performed a retrospective study of cases of severe CAP due to AB over 2 years (January 2022-December 2023). Results: Among 48 patients with CAP caused by AB, 14 cases met severe criteria. Most patients are male (13/14), have an average age of 70, have a history of smoking, chronic lung disease (57.4%), and two or more risk factors (>90%). All severe cases appeared during the dry season months in Ho Chi Minh City from October to April of the following year. Ten had sputum culture, one was bacteremia positive, and both were three. 13 patients were on invasive mechanical ventilation, 12 had to use vasopressors, the mortality rate was 85.71% (12/14), the antibiotic resistance rate of community AB was high, and resistance was over 60% for most antibiotics. All patients received initial empiric antibiotics including third generation Cephalosporins, carbapenems, quinolones, broad-spectrum penicillin/beta-lactamase inhibitors, and glycopeptides. Conclusions: Severe CAP due to AB mainly occurs in the dry season, with high mortality and antibiotic resistance. The risk factor is mainly related to cigarette smoking, and early diagnosis and antibiotic change can improve mortality.