KẾT QUẢ ĐIỀU TRỊ UNG THƯ BUỒNG TRỨNG LOẠI TẾ BÀO HẠT TẠI BỆNH VIỆN K

Abstract

Objective: Describe some clinical and paraclinical characteristics and evaluate the results of treatment of patients with granulosa cell ovarian cancer at K hospital. Research subjects and methods: Retrospective and prospective descriptive study on 44 ovarian tumor patients who were operated on and histopathologically tested at K hospital. Postoperative diagnosis was ovarian granulosa cell tumor eggs from 2014 -2022. Results: The average age was 51.7 ± 13.3 years old, the most common histopathological type was adult granulosa cell tumor (97.2%). The tumor size of granulosa cell tumor is 11.23±5.65cm (from 3.5cm to 25cm). Stage I granulosa cell tumor patients predominate with 50%, stage II accounts for 20.5%, and stage III accounts for 29.5%. Average follow-up time was 47.8 ± 24.7 months (range 10.8-94.4 months), overall survival (OS) and disease-free survival (DFS) rates were 5 years in the patient group. granulosa cell tumors were 90.9% and 79.4%, respectively. Stage I has a greater 5-year DFS than stages II-III (100% vs. 54.1%), the difference is statistically significant with p < 0.001, no residual lesions after surgery have a DFS of 5 More years had residual damage after surgery (94.7% compared to 0%), the difference was statistically significant with p < 0.001. Other factors such as age and tumor size did not have a statistically significant difference with p of 0.091 and 0.706, respectively (p > 0.05). Conclusion: Granulosa cell tumor is a rare type of ovarian cancer with a wide age distribution, with the majority occurring in the early stages and with a good prognosis. Disease stage and remaining lesions after surgery are important prognostic factors for granulosa cell tumors.