ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG BỆNH KAWASAKI VÀ MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN TỔN THƯƠNG ĐỘNG MẠCH VÀNH Ở BỆNH VIỆN SẢN NHI NGHỆ AN

Abstract

Objective: To describe the clinical and paraclinical characteristics of patients with Kawasaki disease and investigate some factors related to coronary artery damage. Research subjects and methods: The cross-sectional study of 62 patients with a confirmed diagnosis of Kawasaki treated at Nghe An Obstetrics and Pediatrics Hospital from January 2019 to July 2021. Results: The most common symptoms are continuous fever for ≥ 5 days, erythema, oral cavity changes (all seen in 100% of cases). Almost cases are of typical disease (93.5%). Most patients have increased white blood cell count (67.7%), increased erythrocyte sedimentation rate (75%), and increased CRP (80%). Coronary artery damage accounts for 38.7%, of which damage to the left coronary artery is 50%, right coronary artery is 33.3% and both coronary arteries are 16.7%. Multivariate analysis results show that CRP and albumin concentrations are independent factors predicting the risk of coronary artery damage. Conclusion: The most common clinical symptoms are fever lasting more than 5 days, skin erythema, and oral cavity changes. Common paraclinical symptoms are erythrocyte sedimentation, increased CRP and white blood cells, and decreased albumin. The prevalence of coronary artery lesions on echocardiography is relatively high (38.7%). CRP and Albumin levels are independent factors predicting the risk of coronary artery damage.