THE VALUE OF VENTRICULOATRIAL CONDUCTION PATTERNS IN RESPONSE TO ADENOSINE IN DIFFERENTIAL DIAGNOSIS OF ATRIOVENTRICULAR NODAL REENTRANT TACHYCARDIA AND ORTHODROMIC RECIPROCATING TACHYCARDIA

Đình Phong Phan , Mạnh Hùng Nguyễn

Main Article Content

Abstract

Aims: This study sought to the value of ventriculoatrial (VA) conduction patterns in response to Adenosine in differential diagnosis of atrioventricular nodal reentrant tachycardia (AVNRT) and orthodromic reciprocating tachycardia (ORT). Results: A total of 45 patients between 2022 and 2023, undergoing electrophysiological study is diagnosed as AVNRT or ORT at Cardiovascular center – E hospital, had assessment of VA conduction during ventricular pacing and adenosine administration. Present of block or lengthening of VA conduction had 96% sensitivity and specificity for diagnose AVNRT. One patient with Adenosine-induced VA block and inducible ORT had decremental AP. Adenosine caused VA block in 2 patients with encentric VA activation due to atypical AV nodal conduction. Persistent VA conduction had 94% sensitivity and specificity for diagnose ORT. Concentric VA conduction persisted in 3 patients with septal AP. Adenosine unmasked free-wall APs in 5 patients by blocking AV nodal conduction, shifting VA activation from concentric and fusion to eccentric. Conclusions: The response of VA conduction to Adenosine is a highly sensitive and specificity method for differential diagnosis of AVNRT and ORT. Besides, in cases of VA conduction is contested by AVN, Adenosine-include block VA nodal conduction can delineate the location of AP atrial insertion site.

Article Details

References

1. AlMahameed S.T., Buxton A.E., and Michaud G.F. New criteria during right ventricular pacing to determine the mechanism of supraventricular tachycardia. Circ Arrhythm Electrophysiol, 2010; 3(6), 578–584.
2. Martínez-Alday J.D., Almendral J., Arenal A., et al. Identification of concealed posteroseptal Kent pathways by comparison of ventriculoatrial intervals from apical and posterobasal right ventricular sites. Circulation, 1994; 89(3), 1060–1067.
3. Lerman B.B., Markowitz S.M., Cheung J.W., et al. Supraventricular Tachycardia: Mechanistic Insights Deduced From Adenosine. Circ Arrhythm Electrophysiol, 2018; 11(12), e006953.
4. Liu C.F., Ip J.E., Cheung J.W., et al. Utility of Pre-Induction Ventriculoatrial Response to Adenosine in the Diagnosis of Orthodromic Reciprocating Tachycardia. JACC Clin Electrophysiol, 2017; 3(3), 266–275.
5. Engelstein E.D., Stein K.M., Markowitz S.M., et al. Posterior fast atrioventricular node pathways: implications for radiofrequency catheter ablation of atrioventricular node reentrant tachycardia. J Am Coll Cardiol, 1996; 27(5), 1098–1105.
6. Ip J.E., Dobesh D.P., Liu C.F., et al. Repetitive oscillating atrial activation during supraventricular tachycardia. J Cardiovasc Electrophysiol, 2014; 25(10), 1137–1139.
7. Chen S.A., Tai C.T., Chiang C.E., et al. Electrophysiologic characteristics, electropharmacologic responses and radiofrequency ablation in patients with decremental accessory pathway. J Am Coll Cardiol, 1996; 28(3), 732–737.
8. Efimova E., Riahi S., Fiedler L., et al. Adenosine sensitivity of retrograde fast pathway conduction in patients with slow-fast atrioventricular nodal reentrant tachycardia: a prospective study. Heart Rhythm, 2014; 11(5), 871–876.