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Date Published: 25/03/2024
Abstract Views: 88
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DOI: https://doi.org/10.51298/vmj.v536i2.8914
Issue
Vol. 536 No. 2 (2024)
Section
Các bài báo
How to Cite
Lê, H. L. H., Trần, T. L., Trịnh , T. H. N., Đại, D. Q., Tạ, T. Đạt, Vũ , B. T. ., Lê, N. A. ., & Nguyễn , H. V. . (2024). THE PREVALENCE OF EBV INFECTION IN NON-SMALL CELL LUNG CANCER PATIENTS. Vietnam Medical Journal, 536(2). https://doi.org/10.51298/vmj.v536i2.8914

THE PREVALENCE OF EBV INFECTION IN NON-SMALL CELL LUNG CANCER PATIENTS

Hạ Long Hải Lê, Thị Lan Trần, Thị Hồng Nhung Trịnh , Diễm Quỳnh Đại, Thành Đạt Tạ, Bình Thư Vũ , Ngọc Anh Lê, Hoàng Việt Nguyễn

Main Article Content

Abstract

Epstein-Barr virus (EBV) is very common virus and associated with several human cancers. However, impact of EBV in non-small cells lung carcinoma responsed to EGFR mutation is not investigated. Our study observed in 100 non-small cell lung carcinoma (NSCLC) samples and found 7% positive with EBV. However, no association between EBV infection in NSCLC with clinical status (p>0.05). Our results showed significant difference between EGFR mutations which responsed to targeted therapy drugs and smoking habit. EGFR mutations were detected lower than in non-smoking patients (p=0.001). Even so, EBV did not display relationship with EGFR mutations in NSCLC patients. Our study is the first described EBV infection in NSCLC patients at VietNam. In future, we can combine targeted therapy responed to EGFR mutations and EBV status in NSCLC patients to improve outcomes.

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References

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