KẾT QUẢ ĐIỀU TRỊ BỆNH NHÂN VIÊM ĐẦU DÀI GÂN NHỊ ĐẦU BẰNG LIỆU PHÁP TIÊM CORTICOID TẠI CHỖ KẾT HỢP VỚI UỐNG DIACEREIN TẠI BỆNH VIỆN TRUNG ƯƠNG THÁI NGUYÊN

Abstract

Objectives: Evaluating the results of long head biceps tendinitis treatment by local corticoid injection combined with oral Diacerein for 3 months in patients treated at the Rheumatology Department, Thai Nguyen National Hospital. Subjects and methods: Interventional study, 72 long head biceps tendinitis patients locally injected corticoid are divided into two groups:  experimental group contains 36 patients  received oral diacerein for 3 months and control group contains 36 patients received oral glucosamin sulfat for 3 months. Result: after 3 months of the treatment, there was an improvement in clinical symtoms and ultrasound images in both groups: clinical symtoms the average VAS decreased from 6.39±0.87 to 1.53±0.91 in the experimental group and from 6.78±0.96 to 2.00±1.09 in the control group, the average SPADI decreased from 59.92±6.05 to 24.14±3.63 in the experimental group and from 62.53±5.40 to 26.33±3.82 in the control group, the average shoulder range of movement increased from 129.72±11.33 to 167.78±8.98 in the experimental group and from 121.94±10.09 to 163.33±7.93 in the control group. 63.9% of the experimental group and 55.6% of the control group had normal ultrasound images after 3 months of the treatment. In the group using diacerein, the incidence of side effects was significantly higher than in the control group, the most common being loose stools (p<0,05). Conclusion: Local corticoid injection therapy combined with oral diacerein or glucosamine sulfate for 3 months significantly improved clinical and ultrasound images of the biceps tendon, however side effects in the diacerein group were significantly more than in the glucosamine sulfate group.