THE STUDY WAS TO EVALUATE THE EFECTIVENESS OF USING ANTIVENOM SERUM IN PATIENT BITTEN BY TRIMESURUS ALBOLARIS AT NGHE AN FRIENDSHIP GENERAL HOPITAL

Đức Phúc Nguyễn , Văn Thủy Nguyễn

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Abstract

Methods: Trimesurus Albolabris bites cause a variety of diseases, local symptoms are very mild but the whole body is very severe, many cases fall into disseminated intravascular coagulation and death. Specific treatment with antivenom is the best method. Objective: To evaluate the effectiveness of using antivenom serum in patients bitten by Trimesurus Albolabris at Nghe An General Hospital. Subjects and methods: A prospective, cross-sectional study on 38 Trimesurus Albolabris biting patients from 08/2021 to 08/2022. Results: Symptoms of swelling improved after 12 hours and 24 hours were 81% and 100%, bleeding symptoms improved after 12 hours and 24 hours were 91.7% and 100%. Pain score before treatment was 4.29; after 12 hours it is 3.03 and after 24 hours it is 1.92. Platelet count, PT, aPTT and Fibrinogen improved after 12 hours, 24 hours of antivenom; p < 0.05. Trimesurus Albolabris anti venom serum is safe with a low rate of side effects of 2.6%. Conclusion: Trimesurus Albolabris antivenom improves symptoms of swelling, hemorrhage, reduces local pain, improves coagulation factors and is safe.

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References

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