KẾT QUẢ ĐIỀU TRỊ BỆNH NHÂN THOÁI HÓA KHỚP GỐI CÓ VIÊM MÀNG HOẠT DỊCH BẰNG LIỆU PHÁP TIÊM CORTICOID KẾT HỢP UỐNG DIACEREIN VÀ GLUCOSAMIN TẠI BỆNH VIỆN A THÁI NGUYÊN

Abstract

Objective: to evaluate the treatment results of knee osteoarthritis patients with synovitis by corticoid injection combined with oral diacerein and glucosamine therapy at Thai Nguyen A hospital. Study subjects and methods: A longitudinal follow-up intervention study was conducted on 37 knee osteoarthritis patients with synovitis by corticoid injection combined with oral diacerein and glucosamine therapy at Thai Nguyen A hospital from 10/2022 - 10/2023. Results: The average age of patients was 66.76±10.66. Signs of bobbing of the kneecap decreased after 1 month of treatment, p<0.05. Signs of morning stiffness, limited movement, and bobbing of the kneecap decreased after 3 months and 6 months of treatment, p<0.05. VAS pain score after 1 month treatment was 4.62±0.95; after 3 months of treatment was 3.03±0.76 and after 6 months treatment was 1.49±0.69; p<0.05. The overall WOMAC score after 1 month treatment was 62.89±9.88; after 3 months treatment was 44.70±8.57 and after 6 months treatment was 21.46±6.74; p<0.05. The slight improvement rate after 1 month treatment was 56.8%; after 3 months treatment was 94.6%. After 6 months of treatment, the clear improvement rate was 59.5% and the slight improvement rate was 40.5%. Overall (100.0%) patients did not experience adverse drug reaction. Conclusion: Treating knee osteoarthritis patients with synovitis by corticoid injection combined with oral diacerein and glucosamine therapy have high, long-lasting results and no adverse drug reaction.