ĐÁNH GIÁ HIỆU QUẢ GIẢM ĐAU SAU MỔ LẤY THAI CỦA PARACETAMOL SO VỚI DICLOFENAC TẠI BỆNH VIỆN NHÂN DÂN GIA ĐỊNH

Abstract

Background: The rate of cesarean sections has increased rapidly over the past 20 years. One of the most issues after a cesarean section is posterior pain. In some clinical trials, the application of different analgesic remedies gave a variable analgesic effect. The problem that often arises for obstetricians is whether the analgesic effect of the anal insertion form is comparable to that of the infusion form, especially on the first day after surgery. Objective: Comparison of paracetamol's post-cesarean analgesic effect versus diclofenac based on pain level during the first day after cesarean section. Methods: Prospective cohort study, conducted on 41 pregnant women using diclofenac, and 49 pregnant women using paracetamol from 04/2023 to 06/2023 at Gia Dinh People's Hospital. Results: The analgesic effect of diclofenac and paracetamol in the first day after cesarean section with VAS was 3.6 ± 1.4 and 6.6 ± 1.2, p < 0.00. Comparing the history of cesarean section with VAS was 4.92±2.15 in the group with the old incision and 5.57± 1.73 P = 0.016 in the group that had never had a cesarean section. In the mild-moderate pain group and the severe pain group, there were 2 relevant factors: infant weight at birth was 3182.7 ± 361 g, and 3466.7 ± 655.7 g, P = 0.002, and blood loss was 339.5 ± 70.1 ml and 466.7 ± 200 ml P<0,001. Conclusions: Diclofenac was more effective at analgesic than paracetamol during the first day after cesarean section. There are 3 factors related to the level of pain after cesarean section: baby weight at birth, blood loss and history of cesarean section. No undesirable effects of the drug were noted.