ĐÁNH GIÁ MỐI LIÊN QUAN GIỮA CHỈ SỐ SpO2/FiO2 VÀ PaO2/FiO2 Ở BỆNH NHÂN ARDS

Abstract

Objective: To study about the correlation between SpO₂/FiO₂ (S/F) and PaO₂/FiO₂ (P/F)  in patients with ARDS and the factors that affected to this correlation. Methods: In this prospective observational study, we enrolled 90 patients with ARDS who were in Surgical intensive care unit (SICU) at Vietnam – Germany Friendship Hospital. Corresponding measurements of SpO₂ (values ≤ 97%) and PaO₂ measured through arterial blood sampling were compared to determine the relationship between S/F and P/F. S/F threshold values correlating with P/F ratios of 100, 200 and 300 were determined. Results: In the derivation data set (336 measurements), the relationship between S/F and P/F was described by the following equation: S/F = 62,8 + 0,87 × (P/F) [p<0,001; r = 0,931). The S/F ratio threshold values of 138, 236 and 320 resulted in 96,6% sensitivity with 95,4% specificity; 88,7% sensitivity with 96,2% specificity and 86,4% sensitivity with 93,1% specificity respectively, for P/F ratios of 100, 200 and 300. Factors that may affected this relationship include: ARDS severity, PEEP level, vasoactive doses and causes of ARDS. Conclusions: S/F ratios correlate with P/F ratios. S/F ratios of 138; 236 and 320 correlate with P/F ratios of 100; 200 and 300, respectively, for diagnosing and following up patients with ARDS.