GASTRO INTESTINAL STROMAL TUMOR OF THE PANCREAS: A CASE REPORT AND REVIEW OF THE LITERATURE

Nguyên Hưng Thái

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Abstract

Study aim: Evaluation of clinical and paraclinical feature of gastrointestinal stromal tumor originating from Pancreas (Extra GIST),  the surgical  result   and revew of the literature. Medical Record: Female aged 60 years olds, admission in K hospital with  vague abdominal pain in left quadrant area, weight loss. The tumor was not palpable on physical examination. CT.Scan revealed a tumor 55-50 cm in diameter located in body-tail of pancreas. Gastroscopy not showed any tumor. Intra operation lesion: Tumor mesuared 6-8 cm originating from body and tail of pancreas. The posterior gastric wall was intact. Surgical Procedure: Left body-tail pancreatec-splenectomy with tumor. Immunohistomestry: positive with CD 117, DOG1 CD 34, KI 67, < 5 mitotic count /50 HPF. Postoperation was simple. The patient discharged 8 days post operation and was given Imatinib. Conclusion: Extra GIST originating from pancreas is extremely rare (< 5% of total GIST, <1% of solid tumor of pancreas). Our case consolidate the possibility that this rare tumor could involve the pancreas as primary site (23 case reproted) and  GIST originating from pancreas are usually of high risk of malignancy.

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References

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