MỨC ĐỘ ĐỀ KHÁNG KHÁNG SINH CỦA VI KHUẨN STAPHYLOCOCCUS AUREUS ĐƯỢC PHÂN LẬP TẠI BỆNH VIỆN ĐA KHOA THÀNH PHỐ CẦN THƠ NĂM 2019 – 2023

Abstract

Background: Antibiotic resistance in Staphylococcus aureus bacteria is a serious problem in the medical field because it reduces the effectiveness of common antibiotics in treating infections caused by this bacteria. Objective: To find out the level of antibiotic resistance of staphylococcus aureus bacteria isolated at Can Tho City General Hospital from 2019 to 2023. Materials and methods: All Staphylococcus aureus bacteria isolated from all specimens at Can Tho City General Hospital from 2019 - 2023. Results: Staphylococcus aureus was highly sensitive over 95% to the antibiotics Vancomycin, Rifampicin, Quinupristin/Dalfopristin and the highest antibiotic resistance is Benzylpenicillin (94.4%). According to each year, excepted for Tigecycline and Quinupristin/Dalfopristin, the antibiotic resistance rate of Staphylococcus aureus in the remaining 12 antibiotics changed by year and had a statistically significant difference with p<0.05. The antibiotic resistance levels of the two groups MRSA and MSSA were statistically significant for the antibiotics Ciprofloxacin, Levofloxacin, Oxacillin, Benzylpenicillin, Tigecycline, Clindamycin, Erythromycin, Gentamicin, Linezolid and Trimethoprim/Sulfamethoxazole (p<0.001). Conclusion: At Can Tho City General Hospital, Staphylococcus aureus was still highly sensitive to some experimental antibiotics. The results of this study contribute to suggesting appropriate antibiotic selection regimens for patients during treatment.