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Date Published: 15/04/2024
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DOI: https://doi.org/10.51298/vmj.v537i2.9226
Issue
Vol. 537 No. 2 (2024)
Section
Các bài báo
How to Cite
Nguyễn, T. V. A., Nguyễn, T. T., & Vũ, X. G. (2024). INVESTIGATION OF THE ANTIOXIDANT EFFECT OF SECONDARY METABOLITES ISOLATED FROM CANNA INDICA L. RHIZOMES FOR THE TREATMENT AND PREVENTION OF HEART DISEASES. Vietnam Medical Journal, 537(2). https://doi.org/10.51298/vmj.v537i2.9226

INVESTIGATION OF THE ANTIOXIDANT EFFECT OF SECONDARY METABOLITES ISOLATED FROM CANNA INDICA L. RHIZOMES FOR THE TREATMENT AND PREVENTION OF HEART DISEASES

Thị Vân Anh Nguyễn, Thanh Tùng Nguyễn, Xuân Giang Vũ

Main Article Content

Abstract

Canna indica L. is a potential medicinal plant for the treatment and prevention of heart diseases. This study evaluated for the first time the antioxidant effect of secondary metabolites isolated from Canna indica L. rhizomes. The DPPH and ABTS assays were performed for 8 compounds including canindicoside A (1), canindicoide B (2), methyl ester S-(-)-rosmarinic acid (3), isorinic acid (4), stiryst-4-ene-3,6-dione (5), 6β-hydroxystigmast-4-en-3-one (6), ent-kaur-15-ene-19-al-17-oic acid (7) and 16α-hydro-19-ol-ent-kauran-17-oic acid (8). The results showed that compound 3 exhibited the strongest antioxidant effect, followed by compounds 4, 1, 7 and 2. Compound 6 had the lowest antioxidant effect. However, compounds 5 and 8 did not show any antioxidant activity. C. indica rhizome could be a potential natural resource for the investigation of bioactive molecules and the development of dietary supplement products to treat and prevent oxidative stress-related diseases. 

Article Details

Keywords

Antioxidant, Canna indica, phytochemicals, rhizome

References

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