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Date Published: 21/08/2021
Abstract Views: 575
Views PDF: 272
DOI: https://doi.org/10.51298/vmj.v504i2.926
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Vol. 504 No. 2 (2021)
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Các bài báo
How to Cite
Anh Tuấn, T. ., & Thị Thu Hà, N. . (2021). THE ASSOCIATION BETWEEN HEMOSTATIC DISORDER AND ORGAN DYSFUNCTION IN PEDIATRIC SEPTIC SHOCK ADMITTED THE INTENSIVE CARE UNIT AT NATIONAL CHILDREN’S HOSPITAL. Vietnam Medical Journal, 504(2). https://doi.org/10.51298/vmj.v504i2.926

THE ASSOCIATION BETWEEN HEMOSTATIC DISORDER AND ORGAN DYSFUNCTION IN PEDIATRIC SEPTIC SHOCK ADMITTED THE INTENSIVE CARE UNIT AT NATIONAL CHILDREN’S HOSPITAL

Tạ Anh Tuấn1,, Nguyễn Thị Thu Hà2
1 Vietnam National Children's Hospital
2 Hanoi Medical University

Main Article Content

Abstract

Background: Hemostatic disorder is a common complication in septic shock, especially disseminated intravascular coagulation is a risk factor for multi-organ dysfunction leading to an increased mortality. Subjects and methods: 56 children were diagnosed with septic shock at the Intensive Care Unit, National Children's Hospital, from August 2019 to August 2020. Set up a cross-sectional descriptive study. Results: At the time of diagnosis, the coagulation disorders incidence were thrombocytopenia (30.4%), prolonged prothrombin time (60.7%), prolonged partial thromboplastin time (53.6%), abnormal fibrinogen concentration (60.7%), increased D-Dimer (98.2%). The group with >2 organ failure had a lower platelet count, more prolonged endogenous and exogenous coagulation, higher D-Dimer level than the group with 2-organ failure (p < 0.05). Group with DIC>4 was a higher risk of failure of >3 organs (OR=10.5), >4 organs (OR=6.1), >5 organs (OR=6.5) compared with the group with DIC≤4, respectively (p < 0.05). Conclusion: In septic shock, the hemostatic disorder is a common complication. Coagulation disorders increase the risk of multi-organ dysfunction.

Article Details

Keywords

Hemostatic disorder, septic shock, multi-organ dysfunction

References

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