CHARACTERISITCS OF THE CORNEAL ENDOTHELIUM IN PATIENTS WITH PSEUDOEXFOLIATION SYNDROME

Kim Thành Đoàn, Minh Tuấn Lê, Ngọc Vân Anh Lê, Hoàng Long Đặng

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Abstract

Purpose: To investigate epidermoloy, clinical characteristics, and corneal endotelial cells’ parameters in PEX patients. Methods: Cross-sectional study. 100 eyes were separated into 2 groups, with 50 eyes in the PEX group and 50 eyes in the normal group. Patients were examined, and information about epidermology and clinical characteristics was collected. Then, patients were taken for corneal endothelial cell imaging with specular microscopy (NIDEK CEM 530). Results: Age and sex distributions are similar between groups. There was no statistically difference between the PEX and the normal group’s visual acuity, intraocular pressure, anterior chamber depth, and cataract grade parameters. The average endothelial cell density (ECD) of the PEX group was 2513,08 ± 435,94 cells/mm2 and the result for the normal group was 2669,26 ± 298,54 cells/mm2 (p = 0,043). Other endothelial cells’ parameters are similar between 2 groups. Conclusion: Patients presenting with PEX have a lower ECD than controls with similar epidemiological characteristics. Caution should be exercised during intraocular surgery in PEX patients to limit postoperative endothelial decompensation.

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References

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