CLINICAL APPLICATION OF SCORE SYSTEMS IN PREDICTING ACUTE PANCREASITIS OUTCOME

Hữu Quí Nguyễn, Thị Mỹ Dung Võ , Duy Thông Võ

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Abstract

The incidence of acute pancreatitis has continuously increased overtime. The majority patients with acute pancreatitis has the mild form of the disease and recovers with supportive treatment within a few days, but some patients become seriously ill and need to be admitted to the intensive care unit. Although there have been many advances in pathophysiological understanding, diagnosis, and treatment, the mortality rate in severe acute pancreatitis remains high. Therefore, predicting which patients are at risk of severe course for optimal treatment right from the beginning is always one of the pressing issues in the management of patients with acute pancreatitis. Various scoring systems have been proposed to predict the severity of acute pancreatitis, but there is no gold standard prognostic score. Computed tomography is the gold standard in detecting pancreatic necrosis and local complications, but pancreatic necrosis may not be detected during the first 48 hours, limiting the predictive value of this test. This article will review currently available scoring systems, as well as other predictors such as imaging and biomarkers in predicting acute pancreatitis outcome.

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References

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