NGHIÊN CỨU ĐẶC ĐIỂM UNG THƯ VÚ DI CĂN CỘT SỐNG

Abstract

Objective: Breast cancer is the most common type of cancer with about 2.1 million new cases each year in the world and is the leading cause of cancer death in women. This topic aims to identify some characteristics of breast cancer with spinal metastasis. Subjects and methods: Carry out a descriptive study on 54 patients with breast cancer who were diagnosed by histopathology, evaluated for TNM stage and classified based on immunohistochemistry. Results: All patients had the histological type of primary breast lesion as invasive breast carcinoma, of which 98.1% of patients had ductal carcinoma. The level of cancer cell differentiation is moderate (grad 2), accounting for the largest proportion (77.8 %) and 22.2 % of patients have poor cell differentiation (grad 3). No patient in the study had good cell differentiation (grad 1). The majority of patients had a detection time of spinal metastases from the time of breast cancer onset of less than 1 year (48.1%). The average time of appearance of spinal metastases is 3.9 ± 3.2 years, the earliest being at the same time of primary breast cancer onset and the latest being 15 years later. Conclusion: Among distant metastases of breast cancer, bone metastases are the most common, in which spinal metastases occupy an important position in bone metastatic lesions.