CLINICAL CHARACTERISTICS, LABORATORY TESTS AND CARDIAC MAGNETIC RESONANCE IMAGING OF PATIENTS WITH ACUTE MYOCARDITIS AT HANOI MEDICAL UNIVERSITY HOSPITAL
Main Article Content
Abstract
Purpose: Describe clinical characteristics, laboratory tests and cardiac magnetic resonance (CRM) imaging of patients with suspected acute myocarditis at Hanoi Medical University Hospital. Material and methods: Descriptive study conducted at Hanoi Medical University Hospital from June 2022 to June 2023 on patients clinically suspected of acute myocarditis, with laboratory tests and cardiac magnetic resonance imaging. Acute myocarditis was diagnosed based on expanded diagnostic criteria and the Lake-Louise 2009 criteria. Results: There were 7 patients with a mean age of 27.7±14.5; male accounts for 71.4%. The main clinical manifestations were chest pain and fever, accounting for 71.4% and 57.1%, respectively. Troponin T and CRPs increased in all patients. 57.1% of patients had abnormalities on the electrocardiogram. On MRI, 100% of patients showed signs of myocardial edema, the myocardial/striated muscle signal ratio ≥ 4 accounted for 71.4%, mainly in the anterior wall, lateral wall (100%), and septum (85.7%). There were 42.8% of patients with signs of early myocardial enhancement and 85.7% of patients with late myocardial enhancement. 71.4% of patients met the diagnostic criteria according to the Lake Louise 2009 criteria. After treatment, all patients recovered after 2-3 weeks. Conclusion: CRM imaging was an important non-invasive imaging method in diagnosing acute myocarditis with clinical symptoms and laboratory tests.
Article Details
Keywords
myocarditis, cardiac magnetic resonance, myocardial enhancement
References
2. Cundari G, Galea N, De Rubeis G, et al. Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis. Int J Cardiovasc Imaging. 2021;37(4):1395-1404. doi:10.1007/s10554-020-02097-9
3. PGS.TS. TẠ MẠNH CƯỜNG. Viêm Cơ Tim Cấp: Cập nhật Chẩn đoán và Điều trị 2017. Tạp Chí Sức Khoẻ. Published online 2017:58+855.
4. Kawai C. From myocarditis to cardiomyopathy: mechanisms of inflammation and cell death: learning from the past for the future. Circulation. 1999;99(8):1091-1100. doi:10.1161/01.cir.99.8.1091
5. Kindermann I, Barth C, Mahfoud F, et al. Update on myocarditis. J Am Coll Cardiol. 2012; 59(9): 779-792. doi:10.1016/j.jacc.2011. 09.074
6. De Cobelli F, Pieroni M, Esposito A, et al. Delayed gadolinium-enhanced cardiac magnetic resonance in patients with chronic myocarditis presenting with heart failure or recurrent arrhythmias. J Am Coll Cardiol. 2006;47(8):1649-1654. doi:10.1016/j.jacc.2005.11.067
7. Friedrich MG, Marcotte F. Cardiac Magnetic Resonance Assessment of Myocarditis. Circ Cardiovasc Imaging. 2013;6(5):833-839. doi: 10.1161/CIRCIMAGING.113.000416
8. Friedrich MG, Strohm O, Schulz-Menger J, Marciniak H, Luft FC, Dietz R. Contrast media-enhanced magnetic resonance imaging visualizes myocardial changes in the course of viral myocarditis. Circulation. 1998;97(18):1802-1809. doi:10.1161/01.cir.97.18.1802
9. Liu PP, Mason JW. Advances in the understanding of myocarditis. Circulation. 2001; 104(9): 1076-1082. doi:10.1161/hc3401. 095198