NGHIÊN CỨU THỰC TRẠNG SỬ DỤNG KHÁNG SINH VANCOMYCIN TẠI BỆNH VIỆN HỮU NGHỊ ĐA KHOA NGHỆ AN

Abstract

Objective: Analysis the current situation of vancomycin use at Nghe An Friendship General Hospital at 2022. Subjects and methods: A retrospective descriptive study on 304 medical records using Vancomycin at Nghe An General Hospital in the period from January 1, 2022 to December 31, 2022. Results: The average age of the patients was 59 years old, of which men accounted for 65.78%. Discharge results: 74.01% of patients recovered/recovered; 25.99% of patients were seriously ill/returned/died. Vancomycin is mainly indicated empiric (90% indicated for empiric and 10% indicated for bacterial target. 92.11% of patients were assigned to microbiological culture in which 87.5% of patients had positive results. aureus is the most commonly isolated Gram (+)  agent. Up to 72.38% of patients received a loading dose. The maintenance dose regimen for non-dialysis patients used mainly in hospital is 1g/12h and 1g/24h corresponding to glomerular filtration rate ClCr > 50ml/min and 10-50ml/min Conclusion: The rate of isolated MRSA was 84.37% among isolated staphylococci strains. still maintain the sensitivity level of 100% on strains of S. aureus and Enterococcus.Patients were assigned loading dose of vancomycin with the rate: 72.38%.