EFFECTIVENESS AND SAFETY OF DAPAGLIFLOZIN VERSUS EMPAGLIFLOZIN IN TREATMENT HfrEF
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Abstract
Empagliflozin and dapagliflozin are SGLT2i drugs used in the treatment of heart failure, demonstrating benefits in reducing mortality and admission rates compared to placebo in clinical trials. A cross-sectional descriptive study was conducted on 90 patients divided into 3 groups: control group, group using dapagliflozin 10mg and group using empagliflozin 10mg to evaluate the effectiveness and safety of dapagliflozin compared with empagliflozin in treatment. chronic heart failure at Nghe An General Friendship Hospital. The two groups dapagliflozin 10mg and empagliflozin 10mg recorded lower mortality risks than the control group (p<0.05); dapagliflozin 10mg improved symptom frequency higher than the empalifozin 10mg group (p<0.05) and empalifozin 10mg improved quality of life higher than the dapalifozin10mg group (p<0.05).
Article Details
Keywords
heart failure, KCCQ-12, dapagliflozin, empaglìlozin, effectiveness, safety
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