CHARACTERISTICS OF HEMOSTATIC DISORDER IN PEDIATRIC SEPTIC SHOCK PATIENTS ADMITTED INTENSIVE CARE UNIT OF THE NATIONAL CHILDREN’S HOSPITAL

Tạ Anh Tuấn1,, Nguyễn Thị Thu Hà2
1 Vietnam National Children's Hospital
2 Hanoi Medical University

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Abstract

Objectives: To determine the clinical and laboratory characteristics of hemostatic disorder in pediatric septic shock patients admitted to the pediatric intensive care unit of the National Children’s Hospital. Subjects and methods: This observational study recruited 56 cases with septic shock between August 2019 and August 2020. Results: The median age was 7.5 months (range, 1-205 months). The frequency of clinical hemorrhage and thrombosis was 19.7% and 1.8%, respectively. All children were abnormal in at least one of the conventional coagulation parameters; included: hypercoagulability (30.4%), hypocoagulability (16.1%), and mixed tendency (53.5%).  Conclusion: The incidence of coagulation abnormality in pediatric with septic shock was high, though most children without clinical hemorrhage and thrombosis. Therefore, this highlights the need for a combination of clinical and laboratory symptoms in the early identification of hemostatic disturbance relating to appropriate and timing treatment.

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References

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