EXPRESSION OF CYTOKERATIN 20 IN UROTHELIAL CARCINOMA OF BLADDER

Nguyễn Trường Giang1,, Nguyễn Văn Hưng2
1 Viet Tiep Hospital, Haiphong
2 Hanoi Medical University

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Abstract

Objectives To evaluate some features of CK 20 immunomarker and its relationship with histological grade, stage in surgical bladder tumor at Viet Duc hospital. Subjects and research methods: A retrospective study was perform in 99 cases of bladder carcinoma through surgical samples at Viet Duc hospital. Results: CK 20 marker was negative in 32 cases (32.3%), focal positive (<10% tumor cells) had 27 cases (27.3%), diffusely positive had 40 cases (40.4 %). CK 20 marker was related to histological grade with p=0.000<0.05 and related to disease stage with p=0.01<0.05. The relationships are statistically significant.

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References

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