ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ ĐAU THẦN KINH TỌA DO THOÁT VỊ ĐĨA ĐỆM BẰNG TIÊM COLLAGEN GUNA

Abstract

Since 2010, the world medical literature has mentioned the method of collagen injection to treat sciatica pain caused by lumbar disc herniation. Collagen therapy treats pathologies caused by the destruction or overload of all tissues of the musculoskeletal system. Collagen Guna provides tropocollagen substrate for the body to synthesize Collagen as well as stimulates fibroblasts to increase endogenous Collagen to help restore, replace, strengthen and build histological structure of Collagen fibers in collagen-containing organizations. Such as tendons, ligaments, joint capsule, fibrocartilage, muscle and extracellular matrix…. Objective: To evaluate the effectiveness and side effects of collagen injection in the treatment of sciatica. Methods: Prospective, interventional study with longitudinal follow-up for 8 weeks with 30 patients with sciatica caused by disc herniation receiving MD-Lumbar  injection, 4-position para spinal injection and MD - Ischia injection along the path of the sciatic nerve 4 positions with 2 treatments weekly (3 days apart)  for the first 2 weeks and 1 treatment weekly for next 6 consecutive weeks. Results: After 8 weeks of treatment, there was an improvement in VAS score from 6.9 ± 1.1 to 1 ± 0.8 (p < 0.05), Lasègue sign (degrees) increased after treatment, right side 22.3 ± 10 degrees left 20.3 ± 7 degrees (p < 0.05). Lumbar spine extension (NP Schober) increased from 2.4 ± 0.8 cm to 5.1±0.3cm. Average hand-to-hand distance improvement 11.2 ± 5 cm decreased to 1.27 ± 1.2cm (p < 0.05). The improvement in daily operation function increased from 1.1 ± 0.3 to 3.9 ± 0.2 (p < 0.05). There are no patient had allergic reaction (post-injection pruritus), infection as well as anaphylaxis, no patient had increased pain after injection. Conclusion: The injections of Collagen MDs are effective method in treatment sciatica caused by herniated discs and there were no side effect were observed.