GIÁ TRỊ CỦA PHÂN LOẠI PI-RADS VỚI CÁC TỔN THƯƠNG KHU TRÚ TRONG CHẨN ĐOÁN UNG THƯ TUYẾN TIỀN LIỆT TẠI BỆNH VIỆN K

Abstract

Purpose: This study aims to review the value of PI-RADS 2.1 on Magnetic Resoncance Imaging (MRI)  with focal lesions in the diagnosis of prostate cancer. Material and Methods: This prospective study was conducted on 10 patients who were detected focal prostate lesions by MRI and classified in terms of PI-RADS (PR) at the National Cancer Hospital  from August 2020 to July 2021. Systematic prostate lesion were biopsed by endorectal ultrasound guided, then compared with the histopathology findings. The positive predictive values of each PI-RADS category and the sensitivity, specificity, and positive and negative predictive values of PI-RADS in the diagnosis of prostate cancer were calculated. Results: 10 patients have mean age is 68 years old, with urine delivery difficulties accounting about 60%, digial rectal examination found abnormal in 80% of patients. The men of total PSA level is of 35,48 ng/ml. In MRI imaging, the mean of prostate volume is 55g and the most common lesion located in the left transition zone of midprostate, accounting for 50%. The positive predictive values of each PI-RADS categories from PR1 to PR5 were 0%, 0%, 0%, 100% and 100%, respectively. The sensitivity, specificity, and positive and negative predictive values of PI-RADS when considering only the lesions classified as PR4 or PR5 were 100% respectively. Conclusion: PI-RADS on MRI showed both very high specificity and sensitivity for focal lesions in the diagnosis of prostate cancer.