RESULTS OF CLINICAL PHARMACY SERVICE IN VENOUS THROMBOEMBOLISM PROPHYLAXIS IN CRITICAL ILLNESS PATIENTS AT EMERGENCY DEPARTMENT, BACH MAI HOSPITAL
Main Article Content
Abstract
Objective: This study is performed to investigate the effects of clinical pharmacist intervention in venous thromboembolism prophylaxis in critical patients at the Emergency Department, Bach Mai Hospital. Study method: An interventional study about clinical pharmacy activities on hospitalized patients at the Emergency Department. Results: 132 patients before intervention and 178 patients after intervention were included in the study. The rate of patients receiving pharmacological prophylaxis when they met the appropriate criteria increased from 48.7% before intervention to 93% after intervention (p<0.01). The proportion of patients receiving prophylaxis who had dosing adjustments based on renal function and weight increased from 76% to 90.8% (p<0.01). No significant changes in the initiation time of thrombolytic prophylaxis or the rate at which patients got full lengths of prevention according to guidelines were found. Conclusions: Clinical pharmacy activities had positive impacts on promoting rational venous thrombosis prophylaxis in critical patients at the Emergency Department. This model should be considered to apply to more subjects and to other clinical units in the hospital.
Article Details
Keywords
venous thrombosis prophylaxis, critical illness patients, intensive care unit, clinical pharmacist intervention
References
2. Patel R., Cook D. J., et al. (2005), "Burden of illness in venous thromboembolism in critical care: a multicenter observational study", J Crit Care, 20(4), pp. 341-7.
3. Kiều Thị Ngọc Anh, Nguyễn Trung Nghĩa (2022), "Thực trạng dự phòng thuyên tắt huyết khối tĩnh mạch tại Khoa Hồi sức tích cực Bệnh viện E", Tạp chí Y học Việt Nam, 516(2).
4. Hội Hồi sức Cấp cứu và Chống độc Việt Nam (2017), "Dự phòng Thuyên tắc huyết khối tĩnh mạch trên bệnh nhân hồi sức tích cực".
5. Hội Tim mạch học Quốc gia Việt Nam (2022), "Khuyến cáo về chẩn đoán, điều trị và dự phòng thuyên tắc huyết khối tĩnh mạch".
6. Rose Anne (2015), "Anticoagulation Management: A Guidebook for Pharmacists", Springer International Publishing Switzerland.
7. Zhang L., Wang Y., et al. (2023), "Impact of clinical pharmacist services on physicians' guideline compliance and prognosis of patients for venous thromboembolism prophylaxis in ICU", Int J Clin Pharmacol Ther, 61(1), pp. 24-32.
8. Russell D Hull MBBS, MScDavid A Garcia, MDAllison E (2024), "Heparin and LMW heparin: Dosing and adverse effects", UpToDate truy cập ngày 19.02.2023.