KẾT QUẢ ÁP DỤNG GÓI XỬ TRÍ SỚM (1-3 GIỜ) TRONG ĐIỀU TRỊ NHIỄM KHUẨN NẶNG, SỐC NHIỄM KHUẨN TẠI KHOA CẤP CỨU BỆNH VIỆN HỮU NGHỊ ĐA KHOA NGHỆ AN

Abstract

Objective: Evaluate the results of applying 1-hour and 3-hour sepsis time bundles in the treatment of severe sepsis, septic shock at the Emergency Department of Nghe An Friendship General Hospital. Subject and method: Cross-sectional description combined with retrospective and prospective data on evaluation of treatment application of 1-hour and 3-hour sepsis time bundles was performed on 152 patients diagnosed with severe infection and septic shock (according to Sepsis-3 definition qSOFA score ≥ 2). The study was conducted from April 2023 to October 2023. Results: the overall compliance rate with recommendations is 86.9%, compliance with fluid replacement accounts for the rate of 98.7%, compliance with blood lactate measurement is 100%, giving appropriate antibiotics in the first hour is 83.6%, compliance with blood culture is 88. 2. Treatment results: the rate of stable disease transferred to a lower level or healthy discharge from the hospital accounted for 66.5%, the rate of severe disease predicted death, the family asked to return home or died. in the Intensive Care Unit, accounting for 33.5%. There are 37.5% of patients on ventilators, the average stay in the Intensive Care Unit is 5.8 days, the least is 1 day and the longest is 24 days. Conclusion: Initial research results show that the application and monitoring of compliance to achieve the goals in the first 1-3 hours according to the recommendations of SSC 2018 for patients with sepsis and septic shock have achieved quite good results. However, studies with a larger number of patients are needed to more closely evaluate the impact on clinical outcomes.