ĐẶC ĐIỂM CẬN LÂM SÀNG, VI SINH VÀ GIẢI PHẪU BỆNH CỦA NGƯỜI BỆNH VIÊM LOÉT GIÁC MẠC TẠI BỆNH VIỆN MẮT THÀNH PHỐ HỒ CHÍ MINH

Abstract

Background: Corneal ulcers are the most common cause of blindness in Vietnam. But most of the reports focus on evaluating the results of treatment of corneal ulcers, while also examining paraclinical characteristics related to prognostic factors and the suitability of paraclinical results to find microbial agents. birth in diagnosis has not been described much. Objective: Determine the paraclinical, microbiological and pathological characteristics of patients with corneal ulcers at Ho Chi Minh City Eye Hospital. Methods: The study describes a series of cases, retrospectively examining medical records of patients diagnosed with infectious corneal ulcers and treated as inpatients at the Cornea Department, Ho Chi Minh City Eye Hospital. Results: The study found that fungi and bacteria are the most common, of which bacteria account for 40.0% and fungi account for 25.0%. Of the 40 cases, 27 cases involved bacteria causing corneal ulcers. Only 4 cases grew bacteria by culture (accounting for 14.8%). Performing RT-PCR on 26 patient samples, in 14 cases of corneal ulcers with bacteria, 10 cases were positive for bacteria, accounting for 38.5% (10/26) and sensitivity of 71.4. % (10/14). In the study sample, the positive rate of the virus was 23.1%, with 1 case due to Aspergillus niger (3.8%). Conclusion: Laboratory results of fresh examination, culture and RT PCR before and after surgery were not consistent with each other.