MỨC ĐỘ ĐỀ KHÁNG KHÁNG SINH CỦA MỘT SỐ VI KHUẨN GRAM ÂM THƯỜNG GẶP TẠI BỆNH VIỆN ĐA KHOA THÀNH PHỐ CẦN THƠ TỪ NĂM 2019 – 2023

Abstract

Background: Antibiotic resistance among pathogenic bacteria is increasing. Objective: Determine the level of multi-antibiotic resistance of gram-negative bacterial strains isolated at Can Tho City General Hospital. Materials and methods: Cross-sectional description of a total of 2313 strains of gram-negative bacteria isolated from clinical specimens at Can Tho General Hospital from January 2019 to December 2023. Results: Quantity The most specimens collected were in the ICU (62.4%), and the highest proportion of specimens collected in the study was sputum (45.1%). Klebsiella pneumoniae (25.9%) and Escherichia coli (23.6%) were the two most commonly isolated strains of gram-negative bacteria. Acinetobacter baumannii and Pseudomonas aeruginosa were 17.8% and 10.0%. Among the three antibiotic resistance groups, bacteria were mainly concentrated in the super-resistant group. In the all-resistant group, A. baumannii (19.9%) and K. pneumoniae (16.7%) had a higher rate than the remaining strains. Except for Proteus and Stenotrophomonas maltophilia, the antibiotic resistance of each remaining gram-negative bacterial strain changed from year to year and had a statistically significant difference (p<0.05).. Conclusions: Gram-negative bacterial strains isolated at Can Tho City General Hospital had a high rate of antibiotic resistance. Developing a reasonable antibiotic combination plan to effectively treat patients is a necessary issue.