TỈ LỆ ĐỀ KHÁNG KHÁNG SINH CỦA STAPHYLOCOCCUS AUREUS VÀ ESCHERICHIA COLI TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC TRÀ VINH

Abstract

Introduction: Antibiotic resistance poses a significant challenge to the healthcare sector and public health globally, affecting the treatment of infectious diseases. Objective: To determine the culture positivity rate, survey the distribution of common pathogenic bacteria, and assess their antibiotic resistance. Methods: Cross-sectional study, collecting bacterial identification data from various specimens and antibiotic susceptibility results at Tra Vinh University Hospital from September 2022 to August 2023. Results: A total of 71 different patient specimens were cultured, with 50 yielding positive results, accounting for a rate of 70%. Among the cultured bacteria, S. aureus (36%) and E.coli (20%) were the most prevalent. The antibiotic resistance rate of S. aureus to Benzylpenicillin was 100%, over 80% to Erythromycin and Clindamycin, over 70% to Oxacillin and Tetracycline, 50% to Gentamicin, and 44% to Trimethoprim-sulfamethoxazole. S.aureus remained sensitive to Vancomycin, Rifampicin, Linezolid, and Tigecycline. E.coli exhibited 100% resistance to Ampicillin and cefazolin, over 80% to Levofloxacin (90%), Ampicillin-sulbactam, and Ceftriaxone, and over 50% to Amoxicillin-clavulanic acid, Tobramycin, and Trimethoprim-sulfamethoxazole (60%). The bacteria were entirely susceptible to Imipenem. Conclusion: Rational antibiotic use is necessary to limit bacterial drug resistance.