CHARACTERISTICS OF KIDNEY SIZE, FUNCTION, AND DONOR SELECTION PERSPECTIVES IN KIDNEY TRANSPLANTATION FROM LIVING RELATED DONORS AT VIET DUC FRIENDSHIP HOSPITAL

Nguyên Vũ Lê, Quang Nghĩa Nguyễn

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Abstract

Objective: Evaluate the characteristics of kidney size on MSCT (Multi-Slice Computed Tomography), renal function on scintigraphy with 99mTcDTPA, and the selection of donor kidneys, along with blood relations. Patients and methods: Descriptive study involving cross-sectional imaging of 84 healthy individuals with the same blood relation as the kidney recipients. After obtaining 24-hour creatinine clearance assessment, renal morphology was evaluated using MSCT 256 slices, and scintigraphy with 99mTcDTPA was performed from January 2018 to Decembre 2022. Results: The minimum age for kidney donation was 30 years, the maximum was 64 years, with a mean ± SD of 49.49 ± 7.44. Donors aged 41–60 comprised the majority, accounting for 82.15%. The male-to-female ratio among kidney donors was 25/59. In most cases, mothers volunteered to donate kidneys to their offspring, representing 54.76%. The rate of fathers donating to children (23.81%) and siblings donating to each other (21.43%) was relatively equal. The kidney size on MSCT 256 slices was as follows: Right kidney in males: 100.64 ± 7.58 mm, females: 100.05 ± 8.36 mm; Left kidney in males: 100.5 ± 11.03 mm, females: 103.00 ± 11.51 mm. The size of donated kidneys was 100.1 ± 7.79 mm, and the retained kidneys were 102.35 ± 8.89 mm. Renal function on scintigraphy with 99mTcDTPA showed an average glomerular filtration rate (GFR) in both genders of 113.26 ± 14.91 mL/minute. GFR for the right kidney was 55.73 ± 8.02 mL/minute, and for the left kidney, it was 57.53 ± 7.78 mL/minute. The donor kidney function percentage was 48.43 ± 1.92%, and the retained kidney function percentage was 51.57 ± 1.92%. No correlation was found between GFR on scintigraphy and estimated formula. Conclusion: Kidney size on CT scans and functional imaging play a significant role in the selection of kidney donors. The decision to donate a kidney is personalized based on various factors.

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