ADENOCARCINOMA OF BLADDER: 2 CASE REPORT

Anh Tú Đỗ, Huyền Trang Vũ

Main Article Content

Abstract

Bladder adenocarcinoma is a scarce histological variant. Most of reports are single-case and small-series. There are no clearly guideline treatment for this subtype bladder cancer. We present 2 patients with vesical adenocarcinoma. The first patient was a 45-year-old woman with a two- months history of intermittent marcroscopic hematuria. Cystoscopy reveal a fungating tumor with 2.5cm diameter, biopsy result is mucious adenocarcinoma. The patient was diagnosed urachal adenocarcinoma. A partial cystectomy with removal of urachus and umblicious. During surgery, we found a tumor from urachus extend to bladder with volume of 3cm by 4cm and the pathology after surgery was also mucious adenocarcinoma. After 6 months of surgery, there is no recurrence lesion. The second was a 33-year-old man. He presented with symptom of hematuria. The biopsy result on cystoscopy was enteric adenocarcinoma. Upper gastrointestinal scopy and colorectal scopy were performed, but there was no evidence of tumor in the exams. A partial cystectomy was scheduled. The pathological report indicated adenocarcinoma with enteric feature and tumor extend beyond tunica muscularis. After surgery 3 weeks, patient had recovered and urinated normally.

Article Details

References

Dahm P, Gschwend JE. Malignant non-urothelial neoplasms of the urinary bladder: a review. Eur Urol. 2003; 44(6): 672-681. doi:10. 1016/s0302-2838(03)00416-0
2. Grignon DJ, Ro JY, Ayala AG, Johnson DE, Ordóñez NG. Primary adenocarcinoma of the urinary bladder. A clinicopathologic analysis of 72 cases. Cancer. 1991; 67(8):2165-2172. doi: 10. 1002/ 1097-0142(19910415) 67:8<2165: :aid-cncr2820670827>3.0.co;2-m
3. Wright JL, Porter MP, Li CI, Lange PH, Lin DW. Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladder. Cancer. 2006; 107(4):721-728. doi: 10. 1002/cncr.22059
4. Sheldon CA, Clayman RV, Gonzalez R, Williams RD, Fraley EE. Malignant Urachal Lesions. J Urol. 1984; 131(1):1-8. doi: 10.1016/ S0022-5347(17)50167-6
5. Wheeler JD, Hill WT. Adenocarcinoma involving the urinary bladder. Cancer. 1954;7(1):119-135. doi:10.1002/1097-0142(195401)7:1<119::AID-CNCR2820070113>3.0.CO;2-8
6. Johnson DE, Hodge GB, Abdul-Karim FW, Ayala AG. Urachal carcinoma. Urology. 1985; 26 (3): 218-221. doi: 10.1016/0 090-4295(85) 90112-8
7. Edwards PD, Hurm RA, Jaeschke WH. Conversion of Cystitis Glandularis to Adenocarcinoma. J Urol. 1972;108(4):568-570. doi:10.1016/S0022-5347(17)60804-8
8. Mylonas KS, O Malley P, Ziogas IA, El-Kabab L, Nasioudis D. Malignant urachal neoplasms: A population-based study and systematic review of literature. Urol Oncol. 2017;35(1):33.e11-33.e19. doi:10.1016/j.urolonc.2016.07.021
9. Xiaoxu L, Jianhong L, Jinfeng W, Klotz LH. Bladder adenocarcinoma: 31 reported cases. Can J Urol. 2001;8(5):1380-1383.
10. Long-term results of primary adenocarcinoma of the urinary bladder: A report on 192 patients - ScienceDirect. Accessed October 29, 2022. https://www. sciencedirect.com/science/article/abs/pii/S1078143905001201