TÁC DỤNG CỦA CAO UP1 TRÊN TRIỆU CHỨNG LÂM SÀNG CỦA BỆNH NHÂN UNG THƯ PHỔI KHÔNG TẾ BÀO NHỎ GIAI ĐOẠN IIIB-IV

Abstract

Objective: To study the effect of UP1 extract on functional symptoms, pain levels according to the VAS scale and the performance status according to the Kanofsky (KPS) of non small cell lung cancer stage IIIB-IV which treating by Paclitaxel-Carboplatin. Subjects and method: 60 patients with diagnosis of non-small cell lung cancer stage IIIB-IV  were divided into 2 groups. The study group includes 30 patients treated by chemotherapy (Paclitaxel-Carboplatin) combined with orally administered UP1 extract 90ml per day. The control group includes 30 patients treated by Paclitaxel-Carboplatin fomular. The duration of treament in both groups was 3 periods with 21 days per each period. Results: The functional symptoms of patients according to the VAS scale in control group were decreased, the performance status of patients according to the Kanofsky (KPS) in control group were increase. Conclusion: UP1 extract has supporting effect on treating patients with non small cell lung cancer stage IIIB-IV, the functional symptoms of patients and VAS after treatment were decreased statistically significant compared with control group (p < 0,05) the performance status of patients were well improved after treatment.