KHẢO SÁT CHỨNG KHÓ TIÊU CHỨC NĂNG Ở BỆNH NHÂN CÓ BIỂU HIỆN TRÀO NGƯỢC DẠ DÀY THỰC QUẢN

Abstract

Objective: The aim of the study was to evaluate the overlap rate of functional dyspepsia according to ROME IV criteria in patients presenting with gastroesophageal reflux disease. Materials and Methods: A cross-sectional and prospective descriptive study on 295 patients presenting with gastroesophageal reflux disease examined at the Department of Gastroenterology, Gastroenterology - Hepatobiliary Center, Bach Mai Hospital in the period from October 2021. until June 2022. Results: A total of 295 patients presenting with gastroesophageal reflux disease were recruited in this study. The most common age group was 30 to 49 years old, accounting for 58.3% (mean = 42.9, SD = 9.9), male patients accounted for 50.8%, female patients accounted for 49.2%. The rate of overlapping functional dyspepsia in patients with gastroesophageal reflux was 46.8%. The rate of epigastric pain accounted for 81.2% in patients overlap GERD and FD, the postprandial discomfort syndrome 68.8% and the intermediate between the two syndromes accounted for 50.1%. Regarding the association of functional dyspepsia in patients with symptoms of gastroesophageal reflux disease with some risk factors, the results from univariate analysis showed two variables with p value < 0.05: The percentage of women who are often found in functional dyspepsia is higher than that of men, this difference is statistically significant with p = 0.042; Patients with the main complaint of typical gastroesophageal reflux symptoms (epigastric burning, heartburn) were less likely to have overlapping functional dyspepsia compared with the rest of the patients. This is statistically significant with p = 0.016. Conclusion: In fact, the overlap of these two groups of diseases is quite common, causing severe symptoms and affecting the quality of life of patient