EVALUATION OF TREATMENT RESULTS WITH THE BEVACIZUMAB – mFOLFOX6 REGIMEN IN FIRST-LINE TREATMENT FOR STAGE IV COLORECTAL CANCER PATIENTS

Nguyễn Hương Giang Trịnh , Thị Minh Châu Nghiêm, Xuân Anh Nguyễn, Quang Vinh Đặng, Vân Trường La

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Abstract

Objectives: To evaluate the results and the side - effects of the Bevacizumab – mFOLFOX6 regimen in the first-line treatment of stage IV colorectal cancer (CRC) patients. Objects and methods: Retrospective and prospective description with longitudinal follow-up of 41 stage IV colorectal cancer patients according to AJCC 8th who were first - line treated with Bevacizumab – mFOLFOX6 regimen at Military 103 hospital and Central Military Hospital 108 from May 2019 to December 2023. Results: The median progression-free survival (PFS) was 11 months. The side-effects were generally at grades 1-2. Conclusion: The Bevacizumab – mFOLFOX6 regimen in metastatic colorectal cancer treatment was highly effective with manageable side-effects.

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References

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