CONCENTRATIONS OF SOME IMMUNOGLOBULINS IN PEDIATRIC PATIENTS WITH SEVERE SEPSIS TREATED AT THE VIETNAM NATIONAL CHILDREN'S HOSPITAL INTENSIVE CARE UNIT
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Abstract
Objective: To observe some immunoglobulin concentrations in pediatric sepsis patients. Research objects and methods: This research describes cases involving 138 pediatric patients with sepsis treated at the Intensive Care Unit, National Children's Hospital, from May 2022 to July 2023. Results: 26 patients had decreased Immunoglobulin levels, of which simple reductions in IgM and IgG were 57.7% and 30.8%, respectively. There was an 11.5% decrease in IgG+IgM. In 52 cases of increased Immunoglobulin levels, increased IgA alone accounted for the highest proportion at 44.2%, followed by increased IgM + IgA simultaneously at 23.1%. The lowest increase was simultaneous IgA + IgG, with 1.9%. Both (IgA + IgG IgM) increased in 17.3%. Conclusion: In pediatric severe sepsis, there were changes in increased and decreased concentrations of some immunoglobulins (IgG, IgM, and IgM). However, there was no difference in the IgG, IgM, and IgA levels between the two sepsis groups with shock and without shock.
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Keywords
Immunoglobulin, severe sepsis
References
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