ĐỊNH LƯỢNG BIỂU ĐỒ KHẾCH TÁN BIỂU KIẾN TRÊN MRI PHÂN BIỆT U TINH HOÀN LÀNH TÍNH VÀ ÁC TÍNH

Abstract

apparent diffusion coefficient (ADC) histogram in distinguishing benign and malignant testicular masses using the Volume-Of-Interest (VOI) method applied to the entire tumor volume. Materials and Methods: A retrospective study involving 40 testicular masses imaged with contrast-enhanced MRI of the scrotal region. Surgical intervention was performed, resulting in 7 benign and 33 malignant masses. ADC histogram indices (mean, median, maximum, minimum, kurtosis, skewness, entropy, StDev, mpp, upp) were measured using the VOI method applied to the entire tumor volume, and a comparison was made between benign and malignant testicular masses. Results: The mean age of the malignant group was 35.67 ± 10.56, higher than the benign group's 24.57 ± 11.0 (p<0.05). The ADC max, ADC skewness, ADC entropy, and ADC variance values in the benign group were lower than those in the malignant group, while ADC min and ADC uniformity values were higher (p<0.05). Using the VOI method on the entire tumor volume, ADC max, ADC variance, and ADC skewness proved to be reliable in distinguishing benign and malignant testicular masses with cutoff values (Sp, Se, AUC) of 1846.0 (75.8; 100; 0.905), 39198.39 (81.8; 85.7; 0.887), and 0.893 (57.6; 100; 0.797), respectively. Conclusion: ADC histogram with the VOI method applied to the entire tumor volume plays a crucial role in the differential diagnosis of benign and malignant testicular masses