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RESULTS AND PREDICTORS OF GOOD OUTCOME AFTER THROMBECTOMY FOR ISOLATED M2 OCCLUSION: DATA FROM A STROKE CENTER IN VIETNAM
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Abstract
Background and aims: Mechanical thrombectomy (MT) for acute ischemic stroke (AIS) with medium-size vessel occlusions is a matter of controversy. This study aimed to find out the predictors of favorable outcomes 3 months after MT for acute ischemic stroke patients with isolated M2 occlusions at Bach Mai Stroke Center (BMSC). Methods: A cross-sectional retrospective study was conducted at BMSC from January 2021 to May 2022. The AIS patients due to M2 occlusion treated with mechanical thrombectomy with or without intravenous thrombolysis were recruited. The primary endpoint was the rate of favorable outcomes (defined as mRS 0-2). Multivariate regression analysis was performed to find out the predictors of favorable outcomes after 3 months. Results: 52 patients were recruited (males 48.1%; median age 68 (60-76)). The baseline NIHSS and ASPECTS scores were 12 (9-15), and 7 (6-8), respectively. The bridging therapy was applied in 14 (26.9%) patients. After 3 months, 31 (59.6%) patients got favorable outcomes (mRS 0-2). The multivariate regression model revealed that a successful recanalization (mTICI 2b-3) independently related to a 90th-day good outcome (OR=51.33; 95% CI: 3.81-691.02; p=0.003). Conclusion: In this study, a good outcome was observed in 59.6% of AIS patients due to M2 occlusion receiving thrombectomy therapy. A successful recanalization (mTICI 2b-3) was the independent predictor of a favorable outcome after 3 months.
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Keywords
Predictors, Acute ischemic stroke patients due to M2 occlusion, mechanical thrombectomy.
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