ĐẶC ĐIỂM LÂM SÀNG, KẾT QUẢ ĐIỀU TRỊ VÀ MỘT SỐ YẾU TỐ LIÊN QUAN Ở TRẺ EM MẮC VIÊM DẠ DÀY - TÁ TRÀNG CÓ NHIỄM HELICOBACTER PYLORI TẠI BỆNH VIỆN NHI ĐỒNG CẦN THƠ

Abstract

Background: Gastric-duodenal inflammation is a common condition across all age groups, often recurrent and potentially leading to complications such as ulcers or cancer. Children, due to their immature physiology and immune system, may present with different clinical manifestations and treatment responses compared to adults, necessitating a more specific and cautious approach. Objectives: To describe the clinical and paraclinical characteristics and evaluate treatment outcomes, as well as explore related factors in children aged 5-16 years with Helicobacter pylori (H. pylori) infection-related gastritis and duodenitis. Materials and methods: A cross-sectional descriptive study was conducted on children aged 5-16 years diagnosed and treated for H. pylori-infected gastritis and duodenitis at Can Tho Children's Hospital from June 2023 to December 2023. Results: A total of 45 patients were included in the study. The male-to-female ratio was approximately 1/1.4, a mean age of 10.71 ± 2.82 years. Common symptoms included abdominal pain (93.3%), predominantly epigastric pain (83.3%), followed by vomiting (24.4%). Endoscopic results revealed predominantly nodular gastritis (71.1%) mainly located in the antrum (91.1%). A quadruple therapy with Bismuth was chosen for most cases (93.3%). The treatment success rate was 75.6%. The ≤ 10 years age group had a higher treatment failure rate (72.7%) compared to older children (> 10 years) (27.3%) with p = 0.046. Conclusion: H. pylori-infected gastritis and duodenitis in children mostly presents with abdominal pain. Lesions observed through upper gastrointestinal endoscopy are mostly nodular gastritis, with the antrum being the most commonly affected site. The majority of cases were successfully treated, although the ≤ 10 years age group was associated with a higher risk of treatment failure.