NGHIÊN CỨU TÌNH HÌNH, MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN TĂNG ACID URIC MÁU Ở BỆNH NHÂN ĐỘT QUỴ NÃO CẤP TẠI BỆNH VIỆN ĐA KHOA THÀNH PHỐ CẦN THƠ

Abstract

Objectives: To determine the prevalence of hyperuricemia and identify associated factors in acute stroke patients aged over 40 years at Can Tho General Hospital. Methods: A cross-sectional study was conducted on 80 acute stroke patients aged over 40 years. Plasma uric acid levels were quantified enzymatically in all patients. Results: Of the 80 acute stroke patients studied, 44 (55%) were male and 36 (45%) were female. The mean age of the patients was 68.48 ± 10.938 years. Among them, 76 patients (95%) had ischemic stroke and 4 patients (5%) had hemorrhagic stroke. The prevalence of hyperuricemia in acute stroke patients over 40 years old was 33.75%, with rates of 43.2% in males and 22.2% in females. Uric acid levels were significantly higher in men compared to women (p=0.049). The average serum uric acid concentration was 327.09 ± 122.425 µmol/L in men and 369.68 ± 116.673 µmol/L in women. For ischemic stroke, the average serum uric acid level was 329.46 ± 120.663 µmol/L, and for hemorrhagic stroke, it was 282.10 ± 166.888 µmol/L. The study also found positive correlations between uric acid levels and height, body mass index (BMI), low-density lipoprotein cholesterol (LDLc), creatinine, and weight (r = 0.293, r = 0.261, r = 0.230, r = 0.312, r = 0.456). Hyperuricemia was associated with gender, smoking, alcohol use, hypertension, and BMI (p=0.049, p=0.013, p=0.027, p=0.006, p=0.002). Conclusions: Hyperuricemia is highly prevalent in acute stroke patients over 40 years old and is associated with height, BMI, LDLc, creatinine, and weight.