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THE QUALITY OF LIFE POST RADICAL CYSTECTOMY AND URINARY DIVERSION
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Abstract
Introduction: Radical cystectomy (RC) is a common treatment for bladder cancer, but it often leads to a significant decline in health-related quality of life (HRQOL) for patients. Despite this, there is limited research comparing the HRQOL outcomes of different urinary diversion methods. This study aims to compare the HRQOL outcomes of two commonly used urinary diversion methods. Methods: We conducted a retrospective analysis of female patients who underwent RC with either ileal orthotopic neobladder (IONB) or ileal conduit (IC) for bladder cancer at Binh Dan Hospital between November 2020 and October 2022. Patients were assessed using the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30) and the bladder cancer-specific instrument (QLQ-BLM30). Results: We analyzed HRQOL data from 102 consecutive bladder cancer patients, including 50 with IONB and 52 with IC. Patients in the IONB group were significantly younger than those in the IC group (median age: 58 vs. 65 years, respectively, p<0.05). Multivariate analysis revealed that patients with IONB had better scores for emotional functioning (86 vs. 78, p< 0.05), cognitive functioning (92 vs. 86, p<0.001), constipation (17 vs. 30, p<0.001), and abdominal bloating flatulence (13 vs. 24, p<0.001). However, there was no significant difference in sexual function between the IONB and IC groups (p < 0.05). Conclusions: Patients with ileal orthotopic neobladder had better health-related quality of life outcomes compared to those with ileal conduit diversion. Short-term outcomes regarding sexual function did not significantly differ between the two groups.
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References
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