ROLE OF V1-V3 TRANSITION INDEX IN DIFFERENTIAL DIAGNOSIS OF VENTRICULAR ARRHYTHMIAS IN THE RIGHT AND LEFT VENTRICULAR OUTFLOW TRACT
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Abstract
Introduction: Localization of premature ventricular contraction (PVC) and ventricular tachycardia (VT) on 12-lead electrocardiogram before ablation is essential. Objectives: Evaluation of the role of the V1-V3 transition index in the differential diagnosis of premature ventricular contraction and ventricular tachycardia in the right and left ventricular outflow tract. Subjects and methods: Cross-sectional, retrospective, and prospective descriptive study Results: 80 patients with idiopathic arrhythmias undergoing radiofrequency ablation (RF) were included in the study. Male : female sex ratio was 1 : 3; mean age 52,7 ± 13,5. There are 67,5% (54/80) patients with ventricular arrhythmias originating from the right ventricular outflow tract and 32,5% (26/80) patients having ventricular arrhythmias originating from the left ventricular outflow tract. The point of transition zone of PVC/VT originating from RVOT is higher than LVOT (3,44 ± 0.88 versus 1,96 ± 0.95), the difference is statistically significant with p<0,05. Transition index V1-V3 of PVC/VT from left ventricular outflow tract is lower than right ventricular outflow tract with statistical significance (- 5,22 ± 8,41 versus 2,01 ± 3,39, p<0,05). When analyzing in the group of PVC/VT with transition at V3, the V1-V3 transition index of PVC/VT from LVOT is also statistically significantly lower than the group of PVC/VT at location from RVOT ( -2,06 ± 6,02 versus 2,89 ± 6,43, with p<0,05). The transition index V1-V3 is valuable for discriminating the origin PVC/VT from RVOT and LVOT with a cut-off point of -1,02 and AUC 0,808 (0,683–0,933), with sensitivity and specificity of 89% and 81%, respectively. The V1-V3 transition index is valuable for discriminating the origin PVC/VT from RVOT and LVOT in the transition group at V3 with a cut-off point of 0,13 and AUC 0,917 (0,683–0,933), with sensitivity and specificity of 83% and 100%, respectively. Conclusion: The V1-V3 transition index of the group PVC/VT originating from the LVOT is lower than that of the group PVC/VT originating from the RVOT, with statistical significance. The V1-V3 transition index has a value in discriminating the site of onset of PVC/VT from LVOT and RVOT, with high sensitivity and specificity.
Article Details
Keywords
Premature ventricular contraction, V1-V3 transition index
References
2. Gulletta S, Gasperetti A, Schiavone M, Paglino G, Vergara P, Compagnucci P, et al. Long-Term Follow-Up of Catheter Ablation for Premature Ventricular Complexes in the Modern Era: The Importance of Localization and Substrate. Journal of clinical medicine. 2022;11(21).
3. Hachiya H, Aonuma K, Yamauchi Y, Harada T, Igawa M, Nogami A, et al. Electrocardiographic characteristics of left ventricular outflow tract tachycardia. Pacing and clinical electrophysiology: PACE. 2000;23(11 Pt 2):1930-4.
4. Jiao ZY, Li YB, Mao J, Liu XY, Yang XC, Tan C, et al. Differentiating origins of outflow tract ventricular arrhythmias: a comparison of three different electrocardiographic algorithms. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 2016;49(5):e5206.
5. Yoshida N, Inden Y, Uchikawa T, Kamiya H, Kitamura K, Shimano M, et al. Novel transitional zone index allows more accurate differentiation between idiopathic right ventricular outflow tract and aortic sinus cusp ventricular arrhythmias. Heart rhythm. 2011;8(3):349-56.
6. Asirvatham SJ. Correlative anatomy for the invasive electrophysiologist: outflow tract and supravalvar arrhythmia. Journal of cardiovascular electrophysiology. 2009;20(8):955-68.
7. Phong PĐ. Nghiên cứu điện sinh lý học tim của rối loạn nhịp thất khởi phát từ xoang Valsava và kết quả triệt đốt bằng năng lượng sóng có tần số Radio. Luận văn Tiến sỹ Y Học. 2014.
8. Tanaka Y, Tada H, Ito S, Naito S, Higuchi K, Kumagai K, et al. Gender and age differences in candidates for radiofrequency catheter ablation of idiopathic ventricular arrhythmias. Circulation journal: official journal of the Japanese Circulation Society. 2011;75(7):1585-91.
9. Yamada T, McElderry HT, Doppalapudi H, Murakami Y, Yoshida Y, Yoshida N, et al. Idiopathic ventricular arrhythmias originating from the aortic root prevalence, electrocardiographic and electrophysiologic characteristics, and results of radiofrequency catheter ablation. Journal of the American College of Cardiology. 2008;52(2):139-47.
10. Di C, Wan Z, Tse G, Letsas KP, Liu T, Efremidis M, et al. The V(1)-V(3) transition index as a novel electrocardiographic criterion for differentiating left from right ventricular outflow tract ventricular arrhythmias. Journal of interventional cardiac electrophysiology: an international journal of arrhythmias and pacing. 2019;56(1):37-43.