KHOẢNG TRỐNG GLYCAT HÓA VÀ VI ĐẠM NIỆU Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÍP 2 MỚI CHẨN ĐOÁN TẠI BỆNH VIỆN ĐA KHOA BẠC LIÊU

Abstract

Background: Glycation reflects blood sugar levels. Glycation gaps have shown potential in predicting diabetic vascular complications. Objectives: This study estimated the Glycation gap, microalbuminuria rate, and identified associated factors in newly diagnosed type 2 diabetes patients at Bac Lieu General Hospital. Materials and methods: A cross-sectional study was conducted using total convenience sampling of 222 newly diagnosed type 2 diabetes patients from April 2023 to April 2024 at Bac Lieu General Hospital. Results: The study revealed an average Glycation gap of 0 ± 1.49 and a Microalbuminuria rate of 45.5%. Low HDL-c levels were associated with higher Glycation gap; HbA1c and serum Glucose showed a positive correlation, while Fructosamine showed an negative correlation with the Glycation gap. Hypertension, HbA1c ≥ 7%, and eGFR < 60 ml/min/1.73 m² were independently associated with Microalbuminuria. Conclusion: In newly diagnosed type 2 diabetes patients at Bac Lieu General Hospital, the Glycation gap was associated with HDL-c, HbA1c, serum Glucose and Fructosamine levels. Microalbuminuria was associated with hypertension, HbA1c levels, and eGFR. However, there was no association between the Glycation gap and Microalbuminuria.