Right ventricular strain by speckle tracking echocardiography in patients with end-stage chronic kidney disease undergoing renal transplantation
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Tóm tắt
Objective: To evaluate right ventricular strain by speckle tracking echocardiography in patients with end-stage chronic kidney disease before and 1 month after kidney transplantation. Subjects and methods: The study included 63 patients diagnosed with end-stage chronic kidney disease. All patients received kidney transplantation at Military Hospital 103 from October 2023 to April 2025. They were followed up for 1 month after kidney transplantation. Right ventricular strain was evaluated before and 1 month after successful kidney transplantation. All informed consents were obtained from participants, and the research was approved by the Ethics Council of Military Hospital 103, Military Medical Academy. Results: RV4CLS ( -17.56 ± 4.82 vs -21.14 ± 3.90, p < 0.01) and RVFWLS (-20.59 ± 6.10 vs -24.81 ± 4.58, p < 0,01) 1 month after kidney transplantation improved significantly compared with pre-transplantation. The rate of right ventricular dysfunction group decreased significantly 1 month after transplantation (40.5 vs 13.5 %, p < 0.01). RV4CSL and RVFWSL after transplantation in the pre-transplant pre-emptive treatment group were statistically higher than in the hemodialysis group. RV4CSL had a moderate positive correlation with the time of dialysis before kidney transplantation. RV4CSL had a moderate positive correlation with hemoglobin level before kidney transplantation. Conclusion: RV4CSL and RVFWSL 1 month after kidney transplantation improved significantly compared with pre-transplantation. The rate of the right ventricular dysfunction group also decreased significantly. RV strain was also associated moderately with the type of pretransplant renal replacement therapy, the duration of dialysis, and the hemoglobin level.
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Từ khóa
right ventricular strain, kidney transplantation, speckle tracking echocardiography
Tài liệu tham khảo
2. Lang R. M., Badano L. P., Mor-Avi V., et al., "Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging," J Am Soc Echocardiogr, vol. 28(1), pp. 1-39.e14., 2015.
3. Mukherjee M., Lawrence G. Rudski et al, "Guidelines for the Echocardiographic Assessment of the Right Heart in Adults and Special Considerations in Pulmonary Hypertension: Recommendations from the American Society of Echocardiography," Journal of the American Society of Echocardiography, pp. 38(3):141-186, 2025.
4. James D. Thomas, Edvardsen T., Abraham T. , et al, "Clinical Applications of Strain Echocardiography: A Clinical Consensus Statement From the American Society of Echocardiography Developed in Collaboration With the European Association of Cardiovascular Imaging of the European Society of Cardiology," Journal of the American Society of Echocardiography, vol. Article in press, pp. 1-36, 2025.
5. Khani, M., Tara, A., Shekarkhar, S. et al., "Effect of kidney transplantation on right ventricular function, assessment by 2- dimensional speckle tracking echocardiography.," Cardiovasc Ultrasound , vol. 18 (16), 2020.
6. Lawrence C., Delonais - Parker A., Shah Z. et al., "Association of Right Ventricular Strain with Cardiovascular Outcomes in Kidney Transplant Recipients.," (American Journal of Transplantation — 2025 submission/online, vol. 25(8):1, 2025.
7. Joseph MS., Tinney F., Naik A. et al, "Right Ventricular Dysfunction and Adverse Outcomes after Renal Transplantation," Cardiorenal Med , vol. 11 (2): 109–118., p. 109–118., 2021.
8. Haller MC, Mihaescu R, et al., "Dialysis Vintage and Outcomes after Kidney Transplantation: A Retrospective Cohort Study," Clin J Am Soc Nephrol., vol. 28;12(1):122–130. , 2016.